Liver Function of Lymphoma Patients with Chronic HBV Infection after Chemotherapy / 中国肿瘤临床
Chinese Journal of Clinical Oncology
; (24): 1208-1212, 2009.
Article
em Zh
| WPRIM
| ID: wpr-671401
Biblioteca responsável:
WPRO
ABSTRACT
Objective. To observe the effect of chemotherapy on hepatic function of lymphoma patients with chronic HBV infection. Methods; We used ELISA to detect the serum markers, of HBV and liver function in 207 lymphoma patients and 207 patients with other types of cancer (except pdmary hepatocellular cacinoma). Results: The incidence of HBV infection was higher in lymphoma cancer cases than that in the controlled cases (19.8% vs 9.7%, P=0.004). The incidence of abnormal liver function was higher in lymphoma patients with positive HBsAg than in lymphoma patients without HBsAg (58.5% vs 27.7%, P=0.000). The incidence of ab-normal liver function in lymphoma patients with postive HBsAg was higher than that in patients with other types of cancer with positive HBsAg (58.5 vs 30.0%, P=0.036). The abnormal liver function in lymphoma patients after chemotherapy was associated with HBV infection (P=0.000) but not correlated with age, sex, histological subtype, immune subtype, stage, ECOG PS, and hormone administration. Conclusion: Lymphoma patients with HBV are more likely to have liver function damage after emotherapy.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Clinical Oncology
Ano de publicação:
2009
Tipo de documento:
Article