Investigation of the interaction of polyamidoamine dendrimers with nicotinic acid as solubility enhancer / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice
;
(12): 294-295, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-671485
ABSTRACT
Objective Polyamidoamine(PAMAM) dendrimers enhance the solubility of nicotinic acid. Methods PAMAM dendrimers of generation 1 to 6 were prepared and the effect of pH and concentration of the dendrimers on the solubility enhancement of nicotinic acid was investigated. Results The pH and concentration of the dendrimers influence the solubility enhancement of nicotinic acid. Conclusions Electrostatic interaction between the carboxyl group of the nicotinic acid and the amine groups of the dendrimers is involved.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Rehabilitation Theory and Practice
Ano de publicação:
2002
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS