EXPERIMENTAL. STUDY ON THE CHANGE OF K~+/Na~+ Mg~(2+)/Ca~(2+)、Zn~(2+)/Cu~(2+)RATIO IN CARDIAC MUSCLE WITH ACUTE MYOCARDIAL IN FARCTION / 中国法医学杂志

ABSTRACT

Using the animal model of acute myocardial infarction of rabbit after left coronary artery ligation, the authors studied the reltionship between the change of myocardial K~+/Na~+ ,Mg~(2+)/Ca~(2+), and Zn~(2+)/Cu~(2+) ratio and the time after acute myocardial infarction. The results demonstrated that. (1)the K+/Na~+ and Mg~(2+)/Ca~(2+)ratio dropped with prolongation of time myocardial ischemia. There was significant (P0.05)difference of Zn~(2+)/Cu~(2+) ratio between the experimental groups and the control group, but Zn~(2+)/Cu~(2+) ratio showed a tendency of dropping with prolongation of time of ischemia in the experimental group. At 120 min of myocardial ischemia,the Zn~(2+)/Cu~(2+) ratio was abour 1/2 as those at 15min, 30min, and 60min(P