Effects of deep hypothermia on MAC,cardiac anesthetic index and myocardial stability of valotile anesthetics / 中华麻醉学杂志
Chinese Journal of Anesthesiology
;
(12)1995.
Artigo
em Chinês
| WPRIM
| ID: wpr-673358
ABSTRACT
Objective:
To investigate the effects of deep hypothermia on MAC,cardiac anesthetic index and myocardial stability of valotile anesthetics.Method:
Forty New Zealand white rabbits were randomly divided into 4 groupshalothane, enflurane,isoflurane and sevoflurane. MAC of valotile agents were determined with the test of clamping tail at normal(38 C?0.5 C )and deep hypothermic(23 C?0.5 C )temperatures. The end-tidal valotile agent concentration at which ventricular arrhythmia appeared by increasing valotile agent concentration and stimulating the heart with extrathoracic electric shock(25V 50Hz)were recorded.Result:
MAC of halothane, enflurane,isoflurane and sevoflurane were decreased by average percentage of 5.1,3.6,4.4 and 4.3 per degree from 38 C to 23 C respectively. Cardiac anesthetic indexes during deep hypothermia were 4.4,3.18.6.25 and 4.6. There was significantly higher incidence of ventricular fibrilation in halothane and enflurane groups (100%) than that in isoflurane and sevoflurane groups(40%)under 8 MAC anesthetics.Conclusion:
Isoflurane is the most suitable valotile agent for deep hypothermic anesthesia, while enflurane is the least.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Anesthesiology
Ano de publicação:
1995
Tipo de documento:
Artigo
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