Effect of partial liquid ventilation with perfluorocarbon on the static lung compliance in rat with smoke inhalation injury / 中华麻醉学杂志

ABSTRACT

Objective: To evaluate the effect of partial liquid ventilation with perfluorocarbon on the static lung compliance in rat with smoke inhalation injury. Method: Partial liquid ventilation (PLV)and mechanical ventilation (MV)were set up on rat's model,total static lung compliance (C_(2.94))and low volume static lung compliance (C_(0.49))were measured with hydraulic pressometer,the expansion index(EI)of lung was calculated. Result: There were significant decrease in C_(2.94),C_(0.49) and EI after 6 hours of smoke inhalation injury as compared with control values (P0.05), but in partial liquid ventilation group C_(2.94).C_(0.49) and EI increased obviously compared with those in smoke inhalation injury and MV groups (P