Impact of Metabolic Syndrome on the White Matter Integrity in Alzheimer's Disease Patients : Tract-Based Spatial Statistics Study under 3-Tesla MRI
Journal of Korean Geriatric Psychiatry
;
: 96-101, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-67355
ABSTRACT
OBJECTIVE:
The aim of this study is to determine whether there is any difference in white matter (WM) integrity between Alzheimer's disease (AD) with metabolic syndrome (MetS) and without MetS.METHODS:
Altogether, 30 subjects were finally recruited from the Memory Impairment Clinics of Pusan National University Hospital in Korea. All subjects (AD with MetS n=15, matched AD without MetS for age, gender and year of education n=15) were underwent 3-tesla magnetic resonance imaging scans of diffusion tensor imaging.RESULTS:
The mean fractional anisotropy of the AD with MetS was lower (p<0.05) in right posterior corona radiate, right corticospinal tract and right superior longitudinal fasciculus than that of the AD without MetS.CONCLUSION:
Our findings suggest that WM integrity damage.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tratos Piramidais
/
Imageamento por Ressonância Magnética
/
Anisotropia
/
Educação
/
Imagem de Tensor de Difusão
/
Doença de Alzheimer
/
Substância Branca
/
Coreia (Geográfico)
/
Memória
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Journal of Korean Geriatric Psychiatry
Ano de publicação:
2016
Tipo de documento:
Artigo
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