Cell-proliferative activity and its relationship to the histological type of early gastric cancer / 中国普通外科杂志

ABSTRACT

Objective To evaluate the biological characteristics of gastric carcinoma and non cancer gastric mucosa which might develop to cancer.Methods The DNA content and proliferative activity of cells in 154 patients with primary mucosal gastric cancer and 40 patients with gastric ulcer wese detected by flow cytometric analysis. A total of 154 samples from mucosal gastric carcinomas, 154 samples from normal mucosa adjacent to carcinomas and 40 samples from normal gastric mucosa adjacent to gastric ulcers were subjected to analysis.Results The incidence of DNA aneuploidy of differentiated carcinoma cells (34.3%) was significantly higher than that of undifferentiated carcinoma cells (14.5%, P