Expressions and clinical significance of multidrug resistance associated protein gene (MRP) and lung resistance protein gene (LRP) in hepatocellular carcinoma (HCC) / 中国普通外科杂志

ABSTRACT

Objective To study the expressions and significance of MRP and LRP in HCC. Methods The expressions of two genes were examined in three tissues (54 cases of HCC, 24 para cancer and 12 posthepatitis cirrhosis tissues) by SP immunohistochemical and PCR techniques. Results MRP and LRP were expressed in three tissues, with significantly higher rates in HCC than others (P