Predictive Factors for Valproate Treatment in Childhood Absence Epilepsy / 대한소아신경학회지
Journal of the Korean Child Neurology Society
;
(4): 7-13, 2010.
Artigo
em Coreano
| WPRIM
| ID: wpr-67409
ABSTRACT
PURPOSE:
To determine the clinical and demographic factors associated with long-term remission of valproate(VPA) therapy in childhood absence epilepsy.METHODS:
Fifty-six cases of childhood and juvenile absence epilepsy were identified by reviewing of Electroencephalographic records and medical charts. Thirty-six cases were initially treated with VPA. Factor associated with responsiveness were identified by uni- and mutivariate logistic regression.RESULTS:
Twenty-seven patient achieved long-term remission(75%). Failure to achieve remission was more likely if the initial treatment of VPA had failed than if it was successful(53% versus 90.4%, P<0.02) was also associated with failure of long-term remission. Lamotrigine was more efficacious add-on drug than Ethosuximide(63.6% vs 25% P=0.04).CONCLUSION:
Long-term seizure remission was related to the patient's initial response to VPA.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Convulsões
/
Triazinas
/
Modelos Logísticos
/
Demografia
/
Ácido Valproico
/
Epilepsia Tipo Ausência
/
Epilepsia
Tipo de estudo:
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Child Neurology Society
Ano de publicação:
2010
Tipo de documento:
Artigo
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