Effect of Tianma Gouteng Decoction and Captoprii on Blood Pressure and Inflammatory Factor in Patients with Essential Hyperten-sion / 中医杂志

ABSTRACT

Objective To investigate the effect of Tianma Gouteng Decoction and Captopril on blood pressure and its mechanism in the senile patients with essential hypertension(EH) in the pattern of ascendant liver yang.Methods Eighty cases with EH were ran- domly divided into two groups,with 40 cases in each group.Treatment group was given Tianma Gouteng Decoction and Captopril and the control group was given only Captopril.The treatment was lasted for 4 weeks.Observed were the changes in blood pressure and serum hs-CRP,TNF-?and IL-6.Results There was significant difference in blood pressure change and improvement of clinical symptoms after treatment between the two groups.The level of serum hs-CRP,TNF-?and IL-6 decreased significantly in the treat- ment group.Conclusion Tianma Gouteng Decoction and captopril can decrease blood pressure and serum hs-CRP,TNF-?and IL-6, and the effect was superior to captopril simply.