PREDICTION OF OVULATION BY MEASURING URINARY LUTIENIZING HORMONE / 中华内分泌代谢杂志

ABSTRACT

Diagnostic laparoscopy was carried out 24-72 hours after urinary luteinizing hormone (LH) surge in 54 patients Estradiol (E2) concentration was determined by radioimmunoassay (RIA) in peritoneal fluid and serum Serum progesterone (P) in midluteal phase was determined by RIA.The reliability of predicting ovulation by means of LH surge was evaluated according to the laparoscopic finding of ovulation and the measurements of E2-RIA and P-RIA.Typical findings of ovulation - corpus hemorrhagicum, ovulatory stigma and bloody fluid in cul-de-sac - were observed during laparoscopy in 44 patients among 54 cases with LH surge. Ovulation was confirmed directly by laparoscopy in 44 patients (81.5%). Ovulation was confirmed by combination of laparoscopy and E2 ratio in 47 cases (87%). Predictive rate of LH surge for ovulation and corpus luteum formation was 87% and 98% respectively. Only one patient could not be confirmed to have ovulation and corpus luteum formation by LH surge.Luteinizing hormone enzyme immunoassay (LHEIA) can be started from the 10th day of menstrual cycle without missing the LH surge. LHEIA can be started from the 12th day of cycle in most patients.