CHARGE SELECTIVITY OF PROTEINURIA IN DIABETES / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12)1986.
Artigo
em Chinês
| WPRIM
| ID: wpr-674668
ABSTRACT
The clearance of proteins differing in charge and/or size (IgG4, total IgG and albumin) was evaluated in 95 diabetic patients. Urinary IgG4 values increased in group mi-croalbuminuria. The increased urinary IgG4 excretion correlated significantly with the degree of albuminuria and diabetic retinopathy. Urinary total IgG levels increased obviously only in group with massive macroalbuminuria. The IgG4/total IgG ratio was highest in group mi-croalbuminuria, and its change had a special pattern. Urinary IgG4 and IgG4/total IgG ratio may be sensitive parameters in assessing early protein charge-selectivity impairment and in detecting incipient diabetic nephropathy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Endocrinology and Metabolism
Ano de publicação:
1986
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS