Expression and clinical significance of bcl-2 gene in breast cancer / 中国癌症杂志

ABSTRACT

Purpose:To study the expression level of bcl 2 gene in breast cancer tissues, paracancer tissues, metastatic lymph nodes and normal tissues. To study the relation of the gene expression and tumor formulation, development and clinical significance. Methods:Semi fixed quantity RT PCR was performed in 16 patients to detect the level of bcl 2 gene expression in cancer tissues, paracancer tissues, metastatic lymph nodes and normal tissues. Results:The relative values of mRNA in cancer tissues was 0.264?0.137 and 0.272?0.076 in metastatic lymph nodes and 0.131?0.083 in paracancer tissues were higher than those in normal tissue (0.033?0.031), so the difference was significant( P