Expression of E-cadherin and nm23 in papillary thyroid carcinoma and its clinical significance / 中国癌症杂志
China Oncology
;
(12)2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-674831
ABSTRACT
Purpose:
To investigate the expression of E cadherin and nm23 in papillary thyroid carcinoma (PTC) and its clinical significance.Methods:
The expression of E cadherin and nm23 were detected by SP immunohistochemical technique in 70 paraffin embedded tissue specimens of PTC.Results:
The positive rates of E cadherin and nm23 were 44.3%(31/70) and 62.9%(44/70) respectively. There were close relations between the expression of E cadherin and nm23 and pathological grade, TNM stage and lymph node metastasis, and no difference could be found between the expression of E cadherin and nm23 and size of tumor, sex and age of patients. There was distinct correlation between the expression of E cadherin and nm23. The metastatic rate in the group, which the expression of E cadherin and nm23 were both positive, was 12%(3/25), but in the all negative group, the metastatic rate was 75%(15/20). There was significant difference between the two groups ( P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Oncology
Ano de publicação:
2001
Tipo de documento:
Artigo
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