Expression of TopoⅡ gene in human bladder cancer multidrug-resistant cells / 中国癌症杂志
China Oncology
;
(12)2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-675009
ABSTRACT
Purpose:
To study the expression of TopoⅡ gene in multidrug resistant cells of human bladder cancer.Methods:
The degree of drug resistance was detected by MTT method ;the expression of TopoⅡ gene in cell lines BIU 87/ADM and BIU 87 was detected with reverse transcriptase polymerase chain reaction.Results:
The cell lines BIU 87/ADM were 56.4 times more resistant to ADM than the cell lines BIU 87;the expression of TopoⅡ gene was poorly positive in BIU 87/ADM but strongly positive in BIU 87 cells.Conclusions:
The decreased expression of TopoⅡ gene in BIU 87/ADM cells might contribute to the development of multidrug resistance of human bladder cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Oncology
Ano de publicação:
2001
Tipo de documento:
Artigo
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