Radiation-induced fibrosis in rat lung: Modification by hydroxypiperquin phosphate / 中国癌症杂志
China Oncology
;
(12)2000.
Artigo
em Chinês
| WPRIM
| ID: wpr-675172
ABSTRACT
Purpose:
To evaluate the HPQP as a modifier of radiation-induced pulmonary fibrosis in rats sacrificed 4 months and 6 months separately after a single dose of 0, 15, 20, 25 Gy60Co r rays to the right hemithorax.Methods:
HPQP was administered by a stomach tube 2 times a week after irradiation at a regimen of 100mg/kg. Pulmonary fibrosis was evaluated by lung hydroxyproline( HP) content and histological observation( LM and EM).Results:
The content of lung HP increased with increasing radiation dose. The differences between control group and 20,25 Gy group are significant P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
China Oncology
Ano de publicação:
2000
Tipo de documento:
Artigo
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