Effect of 5?-reductase inhibitor on vascularity in rats with benign prostatic hyperplasia / 中华老年医学杂志
Chinese Journal of Geriatrics
;
(12)2000.
Artigo
em Chinês
| WPRIM
| ID: wpr-675297
ABSTRACT
Objective To evaluate the effect of 5? reductase inhibitor on vascularity of benign prostatic hyperplasia (BPH). Methods Sixty male adult rats were randomly divided into 4 groups (15 per group) normal control, BPH control group, the group of 5? reductase inhibitor treatment during hyperplasia and the group of treatment after hyperplasia. Immunohistochemistry combined with computer assisted image analysis system were performed to examine the expression of factor Ⅷ related antigen, PCNA and VEGF in the prostatic tissue for all rats. Results The microvessel density(MVD) and the expressions of PCNA and VEGF were much less in treatment during hyperplasia and treatment after hyperplusia than that in BPH control group( P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Geriatrics
Ano de publicação:
2000
Tipo de documento:
Artigo
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