Immigration and proliferation of Schwann cells in chemical acellular xenogeneousnerve grafts in rats / 中华显微外科杂志
Chinese Journal of Microsurgery
; (6)2006.
Article
em Zh
| WPRIM
| ID: wpr-676119
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WPRO
ABSTRACT
Objective To observed the immigration and proliferation of Schwann cells in acellular xe- no-nerve graft in rats.Methods The sciatic nerves on the right side of the rats were exposc.d and 0.8cm long segments of the nerves were removed from the mid-thigh level and replaced by 1.0cm long rabbit nerves made acellular through chemical extraction.After 4 months,the immigration and proliferation of Schwann cells in the graft were revealed by HE staining,S-100 immunohistochemieal staining and transmission electromicro- scope.Results In the rats repaired by acellular nerves,regenerated axons upgrow into the graft,and a- round regenerated axons there were abundant cells aligned,the cytoplasm of which were S-100 immunoreac- tive.Electromicroscope observing showed that regenerated axons were surrounded by myelin formed by the mi- grated cells reoccupied the acellular segments.Conclusion The host Schwann cells can immigrate into rab- bit nerve grafts made acellular through chemical extraction and form myelin enwrapping regenerated axons in rats.
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Índice:
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Idioma:
Zh
Revista:
Chinese Journal of Microsurgery
Ano de publicação:
2006
Tipo de documento:
Article