Clinical study of chemotherapy combined with radiotherapy in the treatment of limited-stage small cell lung cancer / 肿瘤研究与临床
Cancer Research and Clinic
;
(6)2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-676744
ABSTRACT
Objective To evaluate the curative effect of chemotherapy combined with radiotherapy for limited-stage small cell lung cancer(LD-SCLC).Methods 34 cases of patients with LD-SCLC were rand- mized into interdigitating chemoradiotherapy group and sequential chemoradiotherapy group.All patients re- ceived four to six cycles of alternating CE(Ccarboplatin 300 mg/m~2 d_1;Eetoposide100 mg d_(1~5)and CAP(C cyclophosphamide 600 mg/m~2 d_(1,8);Aadriamycin 40 mg/m~2 d_1;Pcisplatin 50 mg d_(3~5)chemotherapy,three weeks for a cycle.All patients also received thoracic radiotherapy with conventional fraction,2.0 Gy per frac- tion,five fractions per week.The total dose was 60 Gy.Results In interdigitating chemoradiotherapy group, CR was 64.7%,PR was 29.4%,NR was 5.9% and PD was 0 after chemo-radiation therapy.In sequential chemoradiotherapy group,CR was 23.5%,PR was 52.9%,NR was 23.5% and PD was 0 after chemothera- py,and CR was 58.8%,PR was 35.3%,NR was 5.9% and PD was 0 after radiotherapy.Conclusion The therapeutic effect of chemotherapy combined with radiotherapy for LD-SCLC was satisying.There was no sig- nificant difference in the effect between the two groups.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Cancer Research and Clinic
Ano de publicação:
2006
Tipo de documento:
Artigo
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