Detection of hepatitis C virus RNA in bone marrow mononuclear cells by digoxin-labeled in situ hybridization / 中华传染病杂志
Chinese Journal of Infectious Diseases
;
(12)1997.
Artigo
em Chinês
| WPRIM
| ID: wpr-677090
ABSTRACT
To investigate HCV extrahepiatic infection and replication site as well as its relation with liver damage,bone-marrow mononuclear cells from 20 cases of nutreated chronic hepatitis C virus infect- ed patients were studied by digoxin-labeled in situ hybridization.Positive HCV RNA stained were de- tected in 18 of 20 cases (90%).Negative HCV RNA stained were not detected in any cases.The results suggested that there was HCV RNA in the bone-marrow of the patients with hepatitis C and bone-mar- row could be infected by HCV.But bone-marrow cell is not the HCV replication site.This study has some significance in HCV elucidating the pathogenicity of as well as the pathogenesis of chronic hepatitis C.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo diagnóstico
Idioma:
Chinês
Revista:
Chinese Journal of Infectious Diseases
Ano de publicação:
1997
Tipo de documento:
Artigo
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