Antiproliferation of heparin on breast cancer cells-MCF-7 / 中国药理学通报

ABSTRACT

AIM To observe the antiproliferative action of heparin on breast cancer cell MCF 7. METHODS Human breast cancer cells MCF 7 and MDA MB 231 were cultured and cell number was counted. RESULTS Heparin(40 mg?L -1 ) inhibited obviously the growth of MCF 7, this inhibition was under influence of serum. CONCLUSION Heparin can inhibit the proliferation of cultured MCF 7 in the presence of serum.