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Investigation of androgen receptor gene expression in human peripheral leukocytes / 第二军医大学学报
Academic Journal of Second Military Medical University ; (12)2000.
Artigo em Chinês | WPRIM | ID: wpr-677443
ABSTRACT

Objective:

To investigate androgen receptor (AR) mRNA expression in human peripheral leukocytes.

Methods:

Total RNA was isolated from peripheral leukocytes of healthy men and women, AR mRNA was determined by RT PCR and Northern blot.

Results:

An AR cDNA fragment of the expected size of 390 bp was determined by RT PCR. 9.4 kb AR mRNA was detected by Northern blot, which was consistent with AR mRNA in human prostate reported by Lubahn et al .

Conclusion:

AR mRNA expresses in human peripheral leukocytes, this provides basis for studying the effect of androgen on the function of the human peripheral leukocytes and the changes of AR in pathological stages. [

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Academic Journal of Second Military Medical University Ano de publicação: 2000 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Academic Journal of Second Military Medical University Ano de publicação: 2000 Tipo de documento: Artigo