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Expression of PTN gene in glioma, hepatoma and laryngeal squamous cell carcinoma / 第二军医大学学报
Academic Journal of Second Military Medical University ; (12)2000.
Artigo em Chinês | WPRIM | ID: wpr-677445
ABSTRACT

Objective:

To investigate the role of pleiotrophin (PTN) gene in carcino genesis using cDNA microarray and in situ hybridization.

Methods:

The expression of PTN gene in 5 cases of glioma, 10 laryngeal squamous cell carcinoma, 6 cases of hepatocarcinoma, and normal controls were detected by BioDoor 4096 type cDNA microarray and in situ hybridization.

Results:

The expression of PTN gene in carcinoma samples were significantly higher than in normal controls by cDNA microarray, the results was the same as by in situ hybridization.

Conclusion:

cDNA microarray is an effective technique in analysis of functional study of associated genes in carcinoma. High expression of PTN gene might be correlated with mechanism of multiple carcinoma. [

Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Academic Journal of Second Military Medical University Ano de publicação: 2000 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Idioma: Chinês Revista: Academic Journal of Second Military Medical University Ano de publicação: 2000 Tipo de documento: Artigo