Expression of PTN gene in glioma, hepatoma and laryngeal squamous cell carcinoma / 第二军医大学学报
Academic Journal of Second Military Medical University
;
(12)2000.
Artigo
em Chinês
| WPRIM
| ID: wpr-677445
ABSTRACT
Objective:
To investigate the role of pleiotrophin (PTN) gene in carcino genesis using cDNA microarray and in situ hybridization.Methods:
The expression of PTN gene in 5 cases of glioma, 10 laryngeal squamous cell carcinoma, 6 cases of hepatocarcinoma, and normal controls were detected by BioDoor 4096 type cDNA microarray and in situ hybridization.Results:
The expression of PTN gene in carcinoma samples were significantly higher than in normal controls by cDNA microarray, the results was the same as by in situ hybridization.Conclusion:
cDNA microarray is an effective technique in analysis of functional study of associated genes in carcinoma. High expression of PTN gene might be correlated with mechanism of multiple carcinoma. [
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Academic Journal of Second Military Medical University
Ano de publicação:
2000
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS