Evaluation of the undoubled-blind design in the clinical trial of Chinese herb / 中国临床药理学与治疗学

ABSTRACT

Bias in undoubled blind design in the clinical trial of Chinese herb affects the evaluation of efficacy and safety. With two examples, the paper recommended a "segregation" technique to minimize the bias in investigators during undoubled blind trial. The results showed that this method combined other strict means can achieve the conclusions the same as a double blind trial.