Effects of intravenous long chain triglyceride or long/medium chain triglyceride fat emulsion on lipid mediators during ANP in rats / 肠外与肠内营养
Parenteral & Enteral Nutrition
;
(6)1997.
Artigo
em Chinês
| WPRIM
| ID: wpr-677908
ABSTRACT
Objectives:
To investigate the effects of intravenous LCT or MCT/LCT fat emulsions on the lipid mediators and pancreatic histological changes in ANP rats.Methods:
Forty three male SD rats were randomized to groups as follow.Group A~C were without ANP, group Anormal controls, group Bnormal rats having received lipid based TPN and group Coperation control(OC) group having received the glucose fluid.Group D~F were with ANP,glucose group,Intralipid group and Lipofundin group.The amylase and prostaglandins in serum were determined in group A.Pancreatic histological examinations were also performed.In group B~F,Amylases or prostaglandins in serum were determined at 4,48 and 72 h, and pancreatic histological examination and pathological scoring were also completed.Results:
Intralipid had no effects on serum prostaglandins when it was infused to normal rats.In groups of ANP,intravenous fat emulsion increased the 6 keto PGF 1? ,and PGE 2 concentration in serum at 4 h.Pancreatic hemorrhagic and fat necrosis were significantly reduced in Lipofundin group.Conclusions:
Intravenous fat emulsion does not worsen the damages to pancreas in ANP.MCT/LCT fat emulsion is more suitable for patients with ANP.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Ensaio Clínico Controlado
Idioma:
Chinês
Revista:
Parenteral & Enteral Nutrition
Ano de publicação:
1997
Tipo de documento:
Artigo
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