Inhibitory effect of nitric oxide on hypertrophic response of cardiomyocytes stimulated by stretch in vitro / 第三军医大学学报

ABSTRACT

3?10 -4 mol/L), and the role was persistent if its concentration was kept. Meanwhile, the increase of intracellular free Ca 2+ induced by stretch was also inhibited by NO. Conclusion Cardiocytes hypertrophic response stimulated by stretch could be inhibited by nitric oxide. The inhibitory effect might be due to the decrease of the concentration of intracellular free Ca 2+ .