A novel approach for studying severe acute respiratory syndrome coronavirus genome──RNA interference / 第二军医大学学报

ABSTRACT

The severe acute respiratory syndrome (SARS) has been spreading in nearly 30 countries and regions worldwide recently. In response to its outbreak, many laboratories worldwide collaborated to identify the causative agent of SARS. A new type of coronavirus(named SARS CoV)has been isolated consequently, and the complete genomic sequences of the SARS CoV have been published. It is very important, at this stage, to deeply investigate the functional genome of SARS CoV with modern molecular techniques. As a new gene silencing method at RNA level, the recently established RNA interference will be a useful approach for the studies of SARS CoV genome.