Differentiation and clinical application of human stem cells / 第二军医大学学报

ABSTRACT

Human stem cell is a unique cell population with the ability of self renewal and differentiation. There are many types of stem cells in human embryonic body and adult tissues, and they have crucial functions in human development. The stem cell differentiation is of great importance for the success of stem cell based therapies,whose effectiveness is determined by the intrinsic property of the cells and the cell microenvironment. The studies on the differentiation of human stem cell include the structural property of the cell and the molecular mechanism in vivo and in vitro . The aim of scientists is to gain the renewable and directional differential stem cells in vitro and use them for a variety of human diseases.