Advances in mechanism and therapy of cancer cachexia / 肠外与肠内营养

ABSTRACT

Cancer cachexia patients have severely metabolic disorders. The release of tumor specific cachectic factors and increased synthesis of cytokines will lead to reinforced catabolism、decreased anabolism and increased energy expenditure of the patients. Progressive depletion of host reserves of adipose tissue and protein will lead to decreasing organs function ,and ultimately the failure of the patients.By increasing understanding of the mechanisms involved in cancer cachexia process,the application of mechanism based anticachectic agents will make great improvements in the therapy of cancer cachexia.