Clinical study of the interferon ?-2b combined with kurorinone in the treatment of chronic hepatitis B / 中华传染病杂志
Chinese Journal of Infectious Diseases
; (12)1997.
Article
em Zh
| WPRIM
| ID: wpr-679047
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WPRO
ABSTRACT
Objective To study the efficacy of interferon ? 2b (IFN? 2b) combined with kurorinone in the treatment of chronic hepatitis B. Methods 146 patients with chronic hepatitis B were randomly divided into four groups(A,B,C,D). Based on the similar general treatment(group D),37 patients in group A was treated with IFN ? 2b and kurorinone. However, 37 patients in group B and 36 patients in group C received IFN ? 2b and kurorinone,respectively.Dynamic changes and relationships among liver histopathology,expression of TGF ? in liver tissue and serum levels of TGF ?,HBeAg,HBV DNA were studied using immunohistochemistry,radioimmunoassay and ELISA before and after treatment of IFN ? 2b and kurorinone. Results The score of histological hepatitic fibrosis,expression of TGF ? in liver tissue and serum levels of TGF ?,HBeAg, HBV DNA in group A showed significant lower than in group B and group C ( P
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Infectious Diseases
Ano de publicação:
1997
Tipo de documento:
Article