Studies on chemical constituents from Semiliquidambar cathayensis / 中草药

ABSTRACT

Object To isolate and identiified the chemical constituents from the EtOAc soluble fraction of the rhizome of Semiliquidambar cathayensis Chang with anti inflammatory activity Methods The EtOAc soluble fraction of anti inflammatory activity was determined on the basis of the mouse ear irritant assay by croton oil The chemical constituents were isolated by silica gel column chromatography, and their structures were identiified by IR, MS and NMR spectroscopic methods including HMQC and HMBC experiments Results Four oleanolic acid derivatives, oleanolic acid, 3 oxo olean 12 en 28 oic acid 2?, 3? dihydroxyolean 12 en 28 oic acid, 2?, 3?, 23 trihydroxyolean 12 en 28 oic acid (arjunolic acid); three ellagic acid derivatives, ellagic acid 3, 3′ dimethylether, ellagic acid 3, 3′, 4 trimethylether, and ellagic acid 4 O ? D xylopyranoside 3, 3′ dimethylether, together with ? sitosterol and octadecylic acid were obtained and identified Conclusion All the nine compounds were isolated for the first time from the title plant