quality standard for Compound Bushen Granule / 中成药

ABSTRACT

Objective: To establish the quality control standards for Compound Bushen Granule (CBG) (Radix Astagali, Fructus Psoraleae Semen Cuscutae, Fructus Lycii, etc.). Methods: Radix Astragali, Semen Cuscutae, Fructus Lycii in CBG were identified by TLC, and the content of psoralen and isopsoralen were determined by HPLC. Results: Radix Astragali, Semen Cuscutae, Fructus Lycii could be identified by TLC, the psoralen showed a good linear relationship at a range of 0.0153?g～0.230?g, r=0.9999 , the average recovery was 102.4%, and RSD was 2.7%, respectively; the isopsoralen showed a good linear relationship at a range of 0.0183?g～0.275?g, r=0.9999, the average recovery was 102.4%, and RSD was 2.7% , respectively. Conclusion: The method is accurate and can be used for the quality control of Compound Bushen Granule.