EFFECT OF THE CIGARETTE SMOKING ON LEARNING, MEMORY AND NERVE GROWTH FACTOR OF HIPPOCAMPUS IN DESCENDANTS OF PASSIVE SMOKING PREGNANT RAT / 解剖学报

ABSTRACT

Objective To study the effects of cigarette smoking on learning and memory ability in rat descendants and its mechanism. Methods Spatial water maze test was applied.Nerve growth factor contents in hippocampus was determimed by IRMA. Results The learning and memory abilities were declined and the nerve growth factor contents in the hippocampus were significantly depressed.Conclusion The effects of cigarette smoking on learning and memory function are highly correlated with the changes in nerve growth factor contents in the hippocampus. [