A Case of Progressive Multifocal Leukoencephalopathy in Acquired Immune Deficiency Syndrome Initially Presented with Early Onset Dementia
Dementia and Neurocognitive Disorders
;
: 20-23, 2014.
Artigo
em Coreano
| WPRIM
| ID: wpr-68310
ABSTRACT
Progressive multifocal leukoencephalopathy (PML) is a very rare and often fatal demyelinating disease of central nervous system (CNS), which mostly occurs in patients with immunosuppression such as acquired immunodeficiency syndrome (AIDS) patients, transplant patients and patients receiving chemotherapy. PML usually manifests with acute or subacute neurologic deficit. and its late diagnosis may lead death or significant permanent disability. We report a 33-year old man diagnosed with PML in AIDS, who initially presented with gradual onset of dementia. Most symptoms of PML were progressed rapidly for several months, and characterized by focal neurological symptoms. On the other hand, we were experienced in patients without focal neurological symptoms and ongoing overall cognitive decline slowly. Patients with immunosuppression can be presented in a variety of neurological symptoms, detailed examinations for cognitive functions were needed in early stage of the disease.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sistema Nervoso Central
/
Síndrome da Imunodeficiência Adquirida
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Terapia de Imunossupressão
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Leucoencefalopatia Multifocal Progressiva
/
Doenças Desmielinizantes
/
Demência
/
Tratamento Farmacológico
/
Diagnóstico Tardio
/
Mãos
/
Manifestações Neurológicas
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Humanos
Idioma:
Coreano
Revista:
Dementia and Neurocognitive Disorders
Ano de publicação:
2014
Tipo de documento:
Artigo
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