Changes of the glutamate transporter EAAC1mRNA expression and injuried nerve cell apoptosis in rat with cerebral ischemia/reperfusion injury treated by mild hypothermia / 中华物理医学与康复杂志
Chinese Journal of Physical Medicine and Rehabilitation
;
(12)2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-683524
ABSTRACT
Objective To investigate the changes in the glutamate transporter EEAC1 mRNA expression and the injured nerve cell apoptosis after rat cerebral ischemia/reperfusion injury is treated with mild hypothermia. Methods The middle cerebral arteries(MCA)of Sprague-Dawley rats were occluded for 30 minutes,and reper- fused for 90 minutes.Using DIG-labeled CRNA probe and TUNEL,the positive rate of glutamate transporter EE- AC1 mRNA expression and apoptotic cell rate were determined in the sham-operated group,the control group and the mild hypothermia group,respectively.Results The positive rate of EEAC1 mRNA expression and apoptotic cell rate were significantly lower in sham-operated group than those in the control group(P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Physical Medicine and Rehabilitation
Ano de publicação:
2003
Tipo de documento:
Artigo
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