Studies on antineoplastic constituents from marine bryozoan bugula neritina inhabiting south china sea (IV):Isolation and structural elucidation of bryostatins 8 and 16 / 中国海洋药物
Chinese Journal of Marine Drugs
;
(6)1994.
Artigo
em Chinês
| WPRIM
| ID: wpr-683900
ABSTRACT
Eight active compounds were isolated from Bugula neritina Linnaeus collected off Dapen Bay in Guandong province, guided by P 388 bioassay system by a combination of successive chromatographies and preparative HPLC. By intensive analysis of the data of high resolution 2D NMR spectrum and ESI MS, their structures were elucidated as known bryostatins--bryostatin 4, 5, 6, 8, 10, 11, 16 and 18, among which bryostatin 8 and 16 were for the first time obtained from this animal in South China Sea and they showed significant antineoplastic activities in vitro.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Marine Drugs
Ano de publicação:
1994
Tipo de documento:
Artigo
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