Synthsis of quaternary Ammonium-Glucosamine conjugate / 中国海洋药物
Chinese Journal of Marine Drugs
;
(6)2001.
Artigo
em Chinês
| WPRIM
| ID: wpr-683922
ABSTRACT
Quaternary ammonium glucosamine conjugatewas prepared by a two step procedure.First,condensation of glucosamine hydrochloride with chloro acetic chloride in the presence of potassium bicarbonate in aqueous medium at 0℃ provided the N chloroacetyl derivative in 74% yield.Subsequent reaction of this intermediate with pyridine at 40℃ for 3 days gave the pyridinium conjugate in 71% yield.The structures of compounds were confirmed by IR,NMR spectra and element analysis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Marine Drugs
Ano de publicação:
2001
Tipo de documento:
Artigo
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