Cognitive Function and P300 Potentials in First-Episode Schizophrenia Treated with Quetiapine and Risperidone / 中国心理卫生杂志
Chinese Mental Health Journal
;
(12)1991.
Artigo
em Chinês
| WPRIM
| ID: wpr-684708
ABSTRACT
Objective:
To compare the effects of quetiapine and risperidone on cognitive function of first-episode schizophrenic patients.Methods:
A randomized comparative clinical design was applied to compare the cognitive function of 67 patients with first-episode schizophrenia treated with quetiapine(n=35,25-750mg/d)and risperidone(n=32,1-7rag/d)before and after 12-week treatment.PANSS,WMS and P300 were used to evaluate adverse effects of drags and cognitive function.Results:
The Long-term memory,Short-term memory,Immediate memory,Memory Quotient of first-episode schizophrenia were damaged obviously.Latency periods of P_2、N_2 and P_3 of P_(300) potentials with first-episode schizophrenia group were longer than the control group,The amplitudes of P_2 and P_3 of P_(300) potentials with first-episode schizophrenia group were lower than the control group(P
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo prognóstico
Idioma:
Chinês
Revista:
Chinese Mental Health Journal
Ano de publicação:
1991
Tipo de documento:
Artigo
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