Relationship between retinopathy and urinary albumin/creatinine of hypertensive patients in a community of Suzhou / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

@#AIM: To explore the risk factors of retinal artery stenosis and its relationship with urinary albumin/creatinine in patients with hypertension, so as to provide a basis for prevention of target organ damage. <p>METHODS: In this study, a cross-sectional study was conducted in 1 983 patients with hypertension. According to the fundus examination, 944 patients were divided into normal group and 1 039 patients were divided into abnormal group. Baseline data were collected and urine albumin/creatinine was measured. Analysis of risk factors for retinal artery stenosis and its relationship with urinary albumin/creatinine.<p>RESULTS: There were significant differences in age and diabetes between the two groups(<i>P</i><0.05). Logistic regression showed that age(<i>OR</i>=1.013, <i>P</i>=0.011)and diabetes mellitus(<i>OR</i>=1.352, <i>P</i>=0.008)were risk factors for retinal artery stenosis. Hypertensive retinopathy(HR)detection rate was 95.56%. Grade I and grade II mild lesions were the major ones. The proportion of macroalbuminuria in retinal stenosis group was 65.59%, higher than that in microalbuminuria group(54.21%)and normal group(50.52%). <p>CONCLUSION: Age and diabetes are risk factors for retinal artery stenosis in hypertensive patients. Retinopathy is associated with urinary albumin/creatinine. The community should strengthen health education and early screening of retina and kidney to prevent the progress of the disease.