Endometrial mullerian adenosarcoma after toremifene treatment in breast cancer patients: a case report / 부인종양
Journal of Gynecologic Oncology
;
: 269-272, 2010.
Artigo
em Inglês
| WPRIM
| ID: wpr-6889
ABSTRACT
Toremifene is an anti-estrogen which has been shown to be effective in the treatment of breast cancer, and is thought to be a less uterotrophic agent than tamoxifen. The risk assessment concerning endometrial cancer has been inconclusive because of its rare use up to the mid-1990s. We report a case of an adenosarcoma, which is a very rare type of uterine malignancy, after toremifene treatment for 5 years in a breast cancer patient. After 1 year of toremifene use, the patient had a benign Mullerian adenofibroma. After an additional 4 years of toremifene treatment, the endometrial polypoid lesion was transformed into a Mullerian adenosarcoma. Although toremifene is a promising anti-estrogenic agent in the treatment of breast cancer patients, clinicians should not neglect the possibility of a uterine malignancy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Tamoxifeno
/
Mama
/
Neoplasias da Mama
/
Adenofibroma
/
Neoplasias do Endométrio
/
Toremifeno
/
Adenossarcoma
/
Medição de Risco
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Gynecologic Oncology
Ano de publicação:
2010
Tipo de documento:
Artigo
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