The Safety and Immune-efficacy of Fucoidan from Gagome Kombu (Kjellmaniella crassifolia) on Women with the History of Gynecological Cancer / 日本補完代替医療学会誌
Japanese Journal of Complementary and Alternative Medicine
;
: 29-35, 2018.
Artigo
em Japonês
| WPRIM
| ID: wpr-689441
ABSTRACT
Objective:
Fucoidan is a sulfated polysaccharide in brown seaweeds. Previous studies show that fucoidan from Gagome kombu (GKF) exhibit immune-enhancing capabilities on healthy adults. In this study, we focused on the women with the history of gynecological cancer and evaluated the safety and immune-efficacy of GKF.Methods:
Ten Japanese women subjects were chosen to ingest the test samples (1 drink / day containing 200 mg GKF) for 4 weeks. Before and after ingestion, blood chemistry analysis, hematological analysis, urinalysis and immune analysis were conducted.Result:
Results showed no adverse clinical changes in blood and urinary analysis. In addition, no serious symptoms were observed. Moreover, decrease of serum levels of Eotaxin, IL-7, IL-17 and VEGF were observed.Conclusion:
These results indicate that in the case of women with the history of gynecological cancer, GKF is a safe functional food ingredient.
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Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Japonês
Revista:
Japanese Journal of Complementary and Alternative Medicine
Ano de publicação:
2018
Tipo de documento:
Artigo
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