Impact of inhaled anesthetics on the male reproductive system and its mechanisms: An update / 中华男科学杂志
National Journal of Andrology
;
(12): 272-276, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-689764
ABSTRACT
The safety of occupational exposure to inhaled anesthetics remains a concern among the medical staff in hospitals. Few reports are seen about the impact of inhaled anesthetics on the reproductive system, particularly that of males. Several clinical and basic studies on isoflurane and others suggest that inhaled anesthetics affect the reproductive system of rodents by decreasing the sperm count, inducing sperm morphological abnormality, reducing sperm motility, and changing the levels of reproductive hormones, the underlying mechanisms of which are mainly associated with the alteration of the hypothalamic-pituitary-gonadal axis and DNA damage and apoptosis of reproductive cells. This article reviews the main impacts of inhaled anesthetics on the male reproductive system and the possible mechanisms.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Contagem de Espermatozoides
/
Motilidade dos Espermatozoides
/
Espermatozoides
/
Dano ao DNA
/
Exposição Ocupacional
/
Apoptose
/
Anestésicos Inalatórios
/
Genitália Masculina
/
Isoflurano
Limite:
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2018
Tipo de documento:
Artigo
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