Repeatability and Reproducibility of Quantitative Assessment of the Retinal Microvasculature Using Optical Coherence Tomography Angiography Based on Optical Microangiography / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 407-412, 2018.
Artigo
em Inglês
| WPRIM
| ID: wpr-690641
ABSTRACT
<p><b>OBJECTIVE</b>The aim of this study was to determine the repeatability and reproducibility of optical coherence tomography angiography (OCTA) based on optical microangiography (OMAG) measurements of macular vessels in normal eyes.</p><p><b>METHODS</b>In this prospective cohort study, 40 eyes of 40 healthy volunteers underwent repeated OCTA (Cirrus HD-OCT 5000 angiography system, Carl Zeiss Meditec, Inc.) scans on two separate visit days. On each visit day, the eyes were scanned three times. The following parameters were used to quantitatively describe the OCTA images of the superficial vascular network vessel area density (VAD), vessel skeleton density (VSD), vessel diameter index (VDI), vessel perimeter index (VPI), vessel complexity index (VCI), flux, and foveal avascular zone (FAZ). Coefficient of variation (CV) and intraclass correlation coefficient (ICC) were calculated for evaluating intravisit and intervisit repeatability, as well as interobserver reproducibility.</p><p><b>RESULTS</b>The measurements showed high repeatability [CVs ⪕ 4.2% (intravisit) and ⪕ 4.6% (intervisit)] and interobserver reproducibility (ICCs ⪖ 0.923) for all parameters.</p><p><b>CONCLUSION</b>This study demonstrated good repeatability and reproducibility of OCTA based on OMAG for the measurement of superficial vessel parameters in normal eyes.</p>
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Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Padrões de Referência
/
Retina
/
Vasos Retinianos
/
Processamento de Imagem Assistida por Computador
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Diagnóstico por Imagem
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Angiofluoresceinografia
/
Estudos Prospectivos
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Reprodutibilidade dos Testes
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Estudos de Coortes
/
Tomografia de Coerência Óptica
Tipo de estudo:
Estudo diagnóstico
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Estudo de etiologia
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Estudos de avaliação
/
Estudo de incidência
/
Estudo observacional
/
Fatores de risco
Limite:
Adulto
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Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Biomedical and Environmental Sciences
Ano de publicação:
2018
Tipo de documento:
Artigo
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