Arterial Ageing
Korean Circulation Journal
;
: 73-79, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-69109
ABSTRACT
Arterial ageing is characterized by age associated degeneration and sclerosis of the media layer of the large arteries. However, besides ageing, clinical conditions, which enhance oxidative stress and inflammation act to accelerate the degree of arterial ageing. In this review, we summarized the pathophysiology and contributing factors that accelerate arterial ageing. Among them, we focused on hypertension, the renin-angiotensin-aldosterone system and vascular inflammation which are modifiable causes of the arterial ageing process. Also, novel treatment targets derived from the disease models such as the Hutchinson Gilford Progeria Syndrome were reviewed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Artérias
/
Progéria
/
Sistema Renina-Angiotensina
/
Esclerose
/
Envelhecimento
/
Estresse Oxidativo
/
Aterosclerose
/
Rigidez Vascular
/
Análise de Onda de Pulso
/
Hipertensão
Idioma:
Inglês
Revista:
Korean Circulation Journal
Ano de publicação:
2013
Tipo de documento:
Artigo
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