Level and significance of serum cystatin C in patients with hypertension complicating left ventricular hypertrophy and atherosclerosis / 重庆医学
Chongqing Medicine
;
(36): 1186-1187,1190, 2018.
Artigo
em Chinês
| WPRIM
| ID: wpr-691930
ABSTRACT
Objective To investigate the level and significance of serum cystatin C in the patients with hypertension compli-cating left ventricular hypertrophy and atherosclerosis.Methods A total of 300 patients with essential hypertension in the cardiolo-gy department of Taizhou Municipal Central Hospital from January 2013 to December 2016 were prospectively selected as the study subjects and divided into the group A(hypertensive group,140 cases),group B[hypertension+carotid artery intima-media thickness (IM T)thickening group,75 cases],group C(hypertension+ left ventricular hypertrophy group,45 cases)and group D(hyperten-sion+carotid IMT thickening+left ventricular hypertrophy group,40 cases)according to whether complicating left ventricular hy-pertrophy and carotid atherosclerosis.The patient′s clinical data and serum cystatin C levels were collected and performed the com-parison.Results The level of LDL in the group B and D was higher than that in the group A and group C(P<0.05);the serum cystatin level in the group B,C and D was higher than that in the group A(P<0.05).The serum cystatin level in the group D was higher than that in the group B and C(P<0.05).There was positive correlation between carotid IMT with low-density lipoprotein, creatinine and cystatin C(P<0.05).The serum cystatin C level was positively correlated with left ventricular mass index(LVMI), left ventricular posterior wall thickness(LVPWT)and interval thickness(IVST)(P<0.05).Conclusion The serum cystatin C lev-el in the patients with hypertension is associated with left ventricular hypertrophy and atherosclerosis occurrence.
Texto completo:
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Índice:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chongqing Medicine
Ano de publicação:
2018
Tipo de documento:
Artigo
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