The effect of stereotactic radiosurgery treatment for recurrent high grade glioma with MRI and MRS / 重庆医学
Chongqing Medicine
; (36): 1756-1757,1762, 2018.
Article
em Zh
| WPRIM
| ID: wpr-692018
Biblioteca responsável:
WPRO
ABSTRACT
Objective To evaluate the effect of MRS-assisted stereotactic radiosurgery (SRS) for small recurrent high grade glioma (HGG).Methods A total of 54 patients with recurrent HGG were selected,the tumor diameter was less than 3 cm,the patients were divided into the conventional MRI group of 26 cases,and MRI+MRS group of 28 cases.The target region of the conventional MRI group was defined as the enhanced and short T1,long T2 area;MRI+MRS group was defined as the region of Cho/NAAindex (CNI) ≥1.6 in the surrounding short T1,long T2 and enhanced area.All the patients were followed up at least 12 months,analysed their therapeutic effect.Results Compared with the conventional MRI group,MRS+MRI group margin dose increased (19.46 Gy vs.13.58 Gy),the average diameter of target were smaller (2.6 cm vs.3.0 cm),progression-free survival was longer (6.8 months vs.5.6 months),the 1-year survival rate was higher (78.6% vs.50.0%),and the occurrence rate of brain edema was lower (5 vs.17),the difference was statistically significant (P<0.05).Conclusion MRI+-MRS assisted SRS helps to accurately identify the scope of HGG,its short term effect was superior.
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WPRIM
Idioma:
Zh
Revista:
Chongqing Medicine
Ano de publicação:
2018
Tipo de documento:
Article