Progresses of HRC gene in hepatocellular carcinoma in chidren / 国际儿科学杂志

ABSTRACT

The histidine enriched calcium protein (HRC)is a new type of sarcoplasmic reticulum (SR) regulator of Ca2 + absorption,storage and release,located in the lumen cavity,with a combination of high capacity and low affinity of calcium ions.Recent studies have shown that abnormal expression of HRC plays a key role in the development of hepatocellular carcinoma.This article reviews the role of HRC in hepatocellular carcinoma.