Contribution of the Proximal Nerve Stump in End-to-side Nerve Repair: In a Rat Model
Clinics in Orthopedic Surgery
;
: 90-95, 2009.
Artigo
em Inglês
| WPRIM
| ID: wpr-69280
ABSTRACT
BACKGROUND:
The aim of this study was to evaluate the contribution of the proximal nerve stump, in end-to-side nerve repair, to functional recovery, by modifying the classic end-to-side neurorrhaphy and suturing the proximal nerve stump to a donor nerve in a rat model of a severed median nerve.METHODS:
Three experimental groups were studied a modified end-to-side neurorrhaphy with suturing of the proximal nerve stump (double end-to-side neurorrhaphy, Group I), a classic end-to-side neurorrhaphy (Group II) and a control group without neurorrhaphy (Group III). Twenty weeks after surgery, grasping testing, muscle contractility testing, and histological studies were performed.RESULTS:
The grasping strength, muscle contraction force and nerve fiber count were significantly higher in group I than in group II, and there was no evidence of nerve recovery in group III.CONCLUSIONS:
The contribution from the proximal nerve stump in double end-to-side nerve repair might improve axonal sprouting from the donor nerve and help achieve a better functional recovery in an end-to-side coaptation model.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Axônios
/
Nervo Ulnar
/
Anastomose Cirúrgica
/
Transferência de Nervo
/
Ratos Sprague-Dawley
/
Músculo Esquelético
/
Força da Mão
/
Recuperação de Função Fisiológica
/
Membro Anterior
/
Nervo Mediano
Limite:
Animais
Idioma:
Inglês
Revista:
Clinics in Orthopedic Surgery
Ano de publicação:
2009
Tipo de documento:
Artigo
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