Expression of Rh Glycoproteins in the Mammalian Kidney
Electrolytes & Blood Pressure
;
: 14-19, 2009.
Artigo
em Inglês
| WPRIM
| ID: wpr-69287
ABSTRACT
Ammonia metabolism is a fundamental process in the maintenance of life in all living organisms. Recent studies have identified ammonia transporter family proteins in yeast (Mep), plants (Amt), and mammals (Rh glycoproteins). In mammalian kidneys, where ammonia metabolism and transport are critically important for the regulation of systemic acid - base homeostasis, basolateral Rh B glycoprotein and apical/basolateral Rh C glycoprotein are expressed along the distal nephron segments. Data from experimental animal models and knockout mice suggest that the Rh glycoproteins appear to mediate important roles in urinary ammonia excretion.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Leveduras
/
Glicoproteínas
/
Proteínas
/
Camundongos Knockout
/
Modelos Animais
/
Amônia
/
Homeostase
/
Rim
/
Túbulos Renais Coletores
/
Mamíferos
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Electrolytes & Blood Pressure
Ano de publicação:
2009
Tipo de documento:
Artigo
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