A case of multicentric reticulohistiocytosis / 대한내과학회지
Korean Journal of Medicine
;
: S850-S856, 2004.
Artigo
em Coreano
| WPRIM
| ID: wpr-69293
ABSTRACT
Multicentric reticulohistiocytosis (MRH) is a rare systemic disease, characterized by severe rapidly destructive polyarthritis and erythematous papulonodular skin lesions. This disorder involves primarily skin and joints, but it has been reported to affect nearly every organ system. Histological analyses of skin, mucosa and synovia reveal that multinucleated giant cells and proliferating histiocytes have smooth eosinophilic ground-glass cytoplasm. We report a case of a 46-year-old woman who was presented with multiple arthritis and erythematous patch on the V-neck and hard nodules on both hands, elbows, great toes, and auricles. About 25% of the reported patients with MRH have been associated with cancer, but MRH is not considered to be a paraneoplastic disorder. She has not been found any other malignant disease. She has been treated with NSAIDs, corticosteroid, alendronate, hydroxychloroquine, and low-dose methotrexate. Cyclosporin A was added to achieve complete remission later on. After 6 months, she was more improved in symptoms of multiple arthritis and skin nodules.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Artrite
/
Pele
/
Líquido Sinovial
/
Dedos do Pé
/
Células Gigantes
/
Anti-Inflamatórios não Esteroides
/
Metotrexato
/
Ciclosporina
/
Alendronato
/
Citoplasma
Limite:
Feminino
/
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2004
Tipo de documento:
Artigo
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